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Glucosamine Hydrochloride

Karl Ivanova

Glucosamine hydrochloride and related amino sugars are essential part of our nutrition, since they are the building 'bricks' our joints and cartilage tissues are build from, and the absence of these 'bricks' can result in many subsequent unpleasant processes, as well as in provoking such diseases as osteoarthritis.

There are debates lasting for years what form is better, hydrochloride or sulfate. Whereas the efficacy of both is equal, since it is not the acid component that makes them useful. Thus, to give one's preference to hydrochloride or its sulfate is only a question of economics, convenience and price.

Glucosamine hydrochloride, as well as sulfate is completely ionized when it comes to stomach, thus making all the differences nullified. Chloride part gives but little to acidity level, and thus it doesn't affect people with stomach acidity problems.

Glucosamine hydrochloride is stable and less able to absorb water vapors, hence it is more useful and much more convenient to store and transport. The original problem was to determine whether the cure ability is depending on sulfate ions presence, but the last researches proved it isn't the case. So, generally speaking, any salts derived from harmless inorganic or organic acids able to bind the amino sugars can be suitable. However, glucosamine hydrochloride is much more easily produced and its production is cost efficient.

To conclude, this comparison, one has to pay additional attention to the percentage of active compounds stated for a given form. The only other comment to add is that sulfate salt is in fact a co-crystallized glucosamine hydrochloride and sodium (or potassium) sulfate and thus is 'diluted'. So if you wish to have less diluted and sodium-free form, glucosamine hydrochloride is the obvious choice. Just pay attention to all the instructions to make sure the amount of the active compound is right.

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